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Therefore, in all 7 primary efficacy and safety studies, forzest showed statistically significant improvement in patients ability to achieve an erection sufficient for vaginal penetration and to maintain the erection long enough for successful intercourse, as measured by the iief questionnaire and by sep diaries.

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Pioglitazone, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when duetact is used in combination with insulin.