Nitrofurantoin is contraindicated for people with allergy to the drug s components, anuria inability to urinate , oliguria low volume of excreted urine , moderate or severe renal insufficiency, chronic kidney disease, liver cirrhosis, chronic hepatitis, deficiency of glucose-6-phosphate dehydrogenase, and acute porphyria.
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unlike many drugs, the presence of food or agents delaying gastric emptying can increase the bioavailability of nitrofurantoin oral suspension, presumably by allowing better dissolution in gastric juices.
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apo-nitrofurantoin is an antibacterial agent specific for urinary tract infections.
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