Isoniazid, inh; pyrazinamide, pza; rifampin moderate rifamycins are inducers of hepatic enzymes, and may alter the pharmacokinetics of beta-blockers including propranolol.

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a 4-mo regimen of isoniazid and rifampin is acceptable therapy for adults who have active tuberculosis and who are sputum-smear and culture negative, if there is little possibility of drug resistance see section 1 above .
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if abnor- malities of liver function exceed three to five times the upper limit of normal, discontin- uation of isoniazid should be strongly considered.
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before taking this product, tell your doctor or pharmacist if you are allergic to rifampin or isoniazid; or to other rifamycins such as rifabutin, rifapentine ; or if you have any other allergies.
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isoniazid is an anti-bacterial drug which is used to treat all forms of tuberculosis.
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prevention of deficiency due to isoniazid in high-risk patients 10 to 25 mg po daily.
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